منابع مشابه
Nephron deficit is not required for progressive proteinuria development in the Munich Wistar Frömter rat.
The Munich Wistar Frömter (MWF) rat represents a genetic model with an inherited nephron deficit and exhibits mild hypertension and progressive albuminuria, which is more pronounced in males than females. Previously, we demonstrated in a consomic strain that replacement of a quantitative trait locus on chromosome 6 normalized the nephron deficit and suppressed albuminuria development, suggestin...
متن کاملHereditary proteinuria syndromes and mechanisms of proteinuria.
N Engl J Med 2006;354:1387-401. Copyright © 2006 Massachusetts Medical Society. The inherited forms of proteinuria comprise a heterogeneous group of rare renal diseases in which glomerular dysfunction and proteinuria are prominent. Despite the rarity of hereditary proteinuria syndromes, genetic, biochemical, and structural studies of these diseases have made important contributions to our knowl...
متن کاملSynchronization phenomena in nephron-nephron interaction.
Experimental data for tubular pressure oscillations in rat kidneys are analyzed in order to examine the different types of synchronization that can arise between neighboring functional units. For rats with normal blood pressure, the individual unit (the nephron) typically exhibits regular oscillations in its tubular pressure and flow variations. For such rats, both in-phase and antiphase synchr...
متن کاملGenetics and the nephron.
There have been phenomenal advances in our understanding of renal biology over the last 20 years through our ability to define the genetic mutations causing kidney disease in children. This review will take you through a trip down the nephron and highlight how these conditions may present to the paediatrician and the molecular basis for their biological effects.
متن کاملCALL FOR PAPERS Comparative Genomics Nephron deficit is not required for progressive proteinuria development in the Munich Wistar Frömter rat
Angela Schulz, Jonna Hänsch, Kristina Kuhn, Maria Schlesener, Peter Kossmehl, Jens R. Nyengaard, Norbert Wendt, Matthias Huber, and Reinhold Kreutz Department of Clinical Pharmacology and Toxicology, CharitéCentrum für Therapieforschung, Charité Universitätsmedizin Berlin, Berlin, Germany; and Stereology and Electron Microscopy Research Laboratory and MIND Center, University of Aarhus, Aarhus, ...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2006
ISSN: 1600-6135,1600-6143
DOI: 10.1111/j.1600-6143.2006.01349.x